plinkQC - Genotype Quality Control with 'PLINK'
Genotyping arrays enable the direct measurement of an
individuals genotype at thousands of markers. 'plinkQC'
facilitates genotype quality control for genetic association
studies as described by Anderson and colleagues (2010)
<doi:10.1038/nprot.2010.116>. It makes 'PLINK' basic statistics
(e.g. missing genotyping rates per individual, allele
frequencies per genetic marker) and relationship functions
accessible from 'R' and generates a per-individual and
per-marker quality control report. Individuals and markers that
fail the quality control can subsequently be removed to
generate a new, clean dataset. Removal of individuals based on
relationship status is optimised to retain as many individuals
as possible in the study.